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Cajun Salmon and Shrimp in creamy Cajun sauce with spinach and cheese

Cajun Salmon and Shrimp

This Cajun Salmon and Shrimp recipe features golden-seared salmon and juicy shrimp simmered in a rich, creamy spinach cheese sauce. Bold Cajun spices meet cozy comfort in this elegant one-pan dinner.
Servings 4 servings
Prep Time 10 minutes
Cook Time 15 minutes
Total Time 25 minutes

Equipment

  • large skillet
  • Tongs or spatula
  • cutting board
  • knife
  • measuring cups and spoons

Ingredients

  • 4 salmon fillets (about 6 oz each)
  • 1/2 lb large shrimp, peeled and deveined
  • 2 tbsp Cajun seasoning
  • 2 tbsp olive oil
  • 2 tbsp butter
  • 3 cloves garlic, minced
  • 1/2 cup red onion, minced
  • 1 tbsp flour (optional)
  • 2 cups fresh spinach, roughly chopped
  • 1 cup heavy cream
  • 1 cup chicken broth
  • 1/2 cup grated Parmesan cheese
  • 1/2 cup shredded mozzarella cheese
  • 1 tsp additional Cajun seasoning (optional)
  • salt and pepper to taste

Instructions

  • Pat the salmon fillets and shrimp dry with paper towels and season evenly with Cajun seasoning.
  • Heat the olive oil and butter in a large skillet over medium-high heat. Sear the salmon for 4–5 minutes per side until golden and cooked through. Remove and set aside.
  • In the same skillet, cook the shrimp for 2–3 minutes per side until pink and opaque. Remove and set aside.
  • Add the garlic and red onion to the skillet and sauté until fragrant, about 1 minute. Sprinkle in the flour if using.
  • Stir in the spinach and cook until wilted, then pour in the heavy cream and chicken broth. Bring to a gentle simmer.
  • Add the Parmesan and mozzarella cheeses and stir until melted and smooth. Season with salt, pepper, and extra Cajun seasoning if desired.
  • Return the salmon and shrimp to the skillet, spoon the sauce over the top, and simmer for 1–2 minutes to meld the flavors.

Notes

Store leftovers in an airtight container for up to 2 days. Reheat gently with a splash of milk or broth to loosen the sauce. Finish with fresh herbs or lemon juice to brighten the flavors before serving.

Nutrition

Calories: 687kcalCarbohydrates: 11gProtein: 44gFat: 52gSaturated Fat: 24gPolyunsaturated Fat: 7gMonounsaturated Fat: 17gTrans Fat: 0.2gCholesterol: 199mgSodium: 676mgPotassium: 1151mgFiber: 2gSugar: 4gVitamin A: 4699IUVitamin C: 7mgCalcium: 278mgIron: 3mg
Author: Serine milo
Calories: 687kcal
Course: dinner
Cuisine: Cajun-American
Keyword: Cajun Salmon and Shrimp, cozy dinner, creamy seafood skillet, one pan seafood, spinach cheese sauce